Complement Receptor 3 Ligation of Dendritic Cells Suppresses Their Stimulatory Capacity
نویسندگان
چکیده
منابع مشابه
Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacity.
To activate T cells effectively, dendritic cells (DCs) must provide three separate signals, MHC-Ag, costimulatory molecules (such as CD80 and CD86), and proinflammatory cytokines (such as IL-12). These three signals are up-regulated in the presence of "danger signals" such as LPS or viral nucleic acids. Evidence suggests that DCs providing only the first two of these signals cannot successfully...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2007
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.178.10.6268